Abstract: An area of the Czech Republic in the northeastern part of the Ceská Lípa district has been affected by “in situ” chemical mining of uranium. The risks associated with the contaminants have been assessed and a complex groundwater remediation project has been generated. The remediation alternatives for both the Cenomanian and Turonian aquifers are presented, relative to time requirements, economics, ecological considerations and the elimination of unacceptable risks for the population and environment. Finally, the present progress of remediation and a concept of what is necessary to complete remediation are presented.